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Antigenic Specificity | IFITM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IFITM3 antibody detects endogenous levels of total IFITM3. Function: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral e |
Immunogen | Immunogen: A synthesized peptide derived from human IFITM3 Subcellular Location: Lysosome; Endosome; Plasma Membrane Tissue Specificity: By IFN-alpha and IFNG/IFN-gamma. Predicted Cross Reactivity: Pig, Sheep Similarity: Pig (100%), Sheep (100%) |
Other Names | [1 8U; Fragilis; IFITM3; IFM3_HUMAN; Interferon induced transmembrane protein 3 (1 8U); Interferon Induced Transmembrane Protein 3; Interferon inducible; Interferon inducible protein 1 8U; Interferon Inducible Protein 15; Interferon Inducible Protein Homolog; Interferon-induced transmembrane protein 3; Interferon-inducible protein 1-8U; IP15] |
Gene, Accession # | [IFITM3], Gene ID: 10410, NCBI: NP_066362.2, UniProt: Q01628 |
Catalog # | MBS9608671 |
Price | $240, $280 |
Order / More Info | IFITM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |