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Antigenic Specificity | Connexin 43/GJA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Gap junction alpha-1 protein(GJA1) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: Connexins 43(Cx43), also called GAP Junction Protein, alpha-1(GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 43 (366-382aa RASSRASSRPRPDDLEI), identical to the related rat and mouse sequences. |
Other Names | [Gap junction alpha-1 protein; gap junction protein, alpha 1, 43kDa; Connexin 43; Connexin-43; Connexin43; Cx 43; CX43; CXA1_HUMAN; DFNB38; Gap junction 43 kDa heart protein; Gap junction alpha 1 protein; Gap junction alpha-1 protein; Gap junction protein alpha 1 43kD; Gap junction protein alpha 1 43kDa(connexin 43); Gap junction protein alpha 1 43kDa; Gap junction protein alpha like; GJA 1; Gja1; GJAL; HGNC:4282; HGNC:8112; Oculodentodigital dysplasia; ODD; ODDD; ODOD; SDTY 3; SDTY3; Syndactyly type III], [GJA1; GJA1; HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1; GJAL; Cx43] |
Gene, Accession # | [GJA1], Gene ID: 2697, NCBI: P17302.2, UniProt: P17302 |
Catalog # | MBS175756 |
Price | $315 |
Order / More Info | Connexin 43/GJA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |