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Antigenic Specificity | GZMM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GZMM antibody detects endogenous levels of total GZMM. Function: Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.Similarity: Belongs to the peptidase S1 family. Granzyme subfamily. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Secreted. Cytoplasmic Granule. Granules of large granular lymphocytes. Tissue Specificity: Highly and constitutively expressed in activated natural killer (NK) cells. Predicted Cross Reactivity: Chicken Similarity: Chicken (80%) |
Other Names | [GRAM_HUMAN; Granzyme M (lymphocyte met ase 1); Granzyme M; GranzymeM; GZM M; Gzmm; HU Met 1; HU-Met-1; LMET 1; LMET1; Lymphocyte met ase 1; MET 1; Met 1 serine protease; Met ase; Met-1 serine protease; Met-ase; MET1; Met1 serine protease; Natural killer cell granular protease] |
Gene, Accession # | [GZMM], Gene ID: 3004, NCBI: NP_001245280.1, UniProt: P51124 |
Catalog # | MBS9603893 |
Price | $240, $280 |
Order / More Info | GZMM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |