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Antigenic Specificity | (Mouse) Ehmt2 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Ehmt2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 589-623 amino acids from the Central region of Mouse Ehmt2. Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not req |
Immunogen | n/a |
Other Names | [Histone-lysine N-methyltransferase EHMT2; 211-; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Protein G9a; Ehmt2; Bat8; G9a; Ng36] |
Gene, Accession # | [Ehmt2], Gene ID: 110147, NCBI: NP_001273502.1, UniProt: Q9Z148 |
Catalog # | MBS9209286 |
Price | $165, $370 |
Order / More Info | (Mouse) Ehmt2 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Tachibana M.,et al.Genes Dev. 16:1779-1791(2002). Xie T.,et al.Genome Res. 13:2621-2636(2003). Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009). Brown S.E.,et al.Mamm. Genome 12:916-924(2001). Tachibana M.,et al.J. Biol. Chem. 276:25309-25317(2001). |