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Antigenic Specificity | FOXL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total FOXL2 protein. This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human forkhead box L2 |
Other Names | [BPES; PFRK; POF3; BPES1; PINTO] |
Gene, Accession # | [FOXL2], Gene ID: 668, NCBI: NP_075555.1, UniProt: P58012 |
Catalog # | MBS9405007 |
Price | $255 |
Order / More Info | FOXL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |