Edit |   |
---|---|
Antigenic Specificity | CNTFR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of CNTFR protein. CNTFR encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in CNTFR may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for CNTFR. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human CNTFR protein |
Other Names | [Rabbit CNTFR; Ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha; CNTFR-alpha] |
Gene, Accession # | [CNTFR], Gene ID: 1271, NCBI: P26992.2, UniProt: P26992 |
Catalog # | MBS9708795 |
Price | $130, $220, $325 |
Order / More Info | CNTFR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |