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Antigenic Specificity | MAP4K4 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MAP4K4. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MAP4K4 is the serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. MAP4K4 appears to act upstream of the JUN N-terminal pathway.The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and media |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K4 |
Other Names | [mitogen-activated protein kinase kinase kinase kinase 4 isoform 1; Mitogen-activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; Nck-interacting kinase] |
Gene, Accession # | [MAP4K4], Gene ID: 9448, NCBI: NP_004825, UniProt: O95819 |
Catalog # | MBS3209295 |
Price | $365 |
Order / More Info | MAP4K4 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |