Edit |   |
---|---|
Antigenic Specificity | CD80 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for T-lymphocyte activation antigen CD80(CD80) detection. Tested with WB in Human. Background: Cluster of Differentiation 80(also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28(for autoregulation and intercellular association) and CTLA-4(for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. Reeves et al.(1997) stated tha |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CD80 (57-71aa EELAQTRIYWQKEKK). |
Other Names | [T-lymphocyte activation antigen CD80; CD80 molecule; Activation B7 1 antigen; Activation B7-1 antigen; Activation B71 antigen; B lymphocyte activation antigen B7; B7; B7-1; B7-1 antigen; BB1; CD 80; CD28 antigen ligand 1; CD28 antigen ligand 1 B7 1 antigen; CD28 antigen ligand 1 B71 antigen; CD28LG; CD28LG1; CD80; CD80 antigen; CD80 antigen precursor; CD80 molecule; CD80_HUMAN; Costimulatory factor CD80; CTLA 4 counter receptor B7.1; CTLA-4 counter-receptor B7.1; LAB 7; LAB7; T lymphocyte activation antigen CD80; T-lymphocyte activation antigen CD80], [CD80; CD80; B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1; CD28LG; CD28LG1; LAB7; B7] |
Gene, Accession # | [CD80], Gene ID: 941, NCBI: P33681.1, UniProt: P33681 |
Catalog # | MBS175144 |
Price | $280 |
Order / More Info | CD80 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |