PHD2/prolyl hydroxylase Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PHD2/prolyl hydroxylase |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PHD2 / prolyl hydroxylase Antibody detects endogenous levels of total PHD2 / prolyl hydroxylase. Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at ' Pro-402' and ' Pro-564' , and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. |
| Immunogen | Immunogen: A synthesized peptide derived from human PHD2 / prolyl hydroxylase |
| Other Names | [egl nine homolog 1; Egl nine homolog 1; egl nine homolog 1; egl-9 family hypoxia inducible factor 1; Hypoxia-inducible factor prolyl hydroxylase 2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH-2; Prolyl hydroxylase domain-containing protein 2; PHD2; SM-20] |
| Gene, Accession # | [PHD2], Gene ID: 54583, NCBI: NP_071334.1, UniProt: Q9GZT9 |
| Catalog # | MBS4751050 |
| Price | $335 |
| Order / More Info | PHD2/prolyl hydroxylase Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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