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Antigenic Specificity | Human MVP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | DyLight 488 conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. |
Immunogen | Immunogen: E Coli-derived human MVP recombinant protein (Position: A2-H259). |
Other Names | [Rabbit IgG Human MVP DyLight 488 Conjugated, Flow Validated; Major vault protein; MVP; Lung resistance-related protein; MVP; LRP] |
Gene, Accession # | [MVP], Gene ID: 9961, NCBI: NP_001280133.1, UniProt: Q14764 |
Catalog # | MBS1751264 |
Price | $330 |
Order / More Info | Human MVP Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: MVP major vault protein. 2. Izquierdo MA, Scheffer GL, Flens MJ, Schroeijers AB, van der Valk P, Scheper RJ (Jun 1996). Major vault protein LRP-related multidrug resistance. European Journal of Cancer. 32A (6): 979-84. |