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Antigenic Specificity | p53R2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | p53R2 Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and gamma-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression. |
Immunogen | Immunogen: p53R2 antibody was raised against a 16 amino acid peptide near the amino terminus of human p53R2. Buffer: p53R2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [p53R2; P53R2; MTDPS8A; MTDPS8B; P53R2; Ribonucleoside-diphosphate reductase subunit M2 B; TP53-inducible ribonucleotide reductase M2 B; p53R2; ribonucleotide reductase M2 B (TP53 inducible)], [RRM2B; RRM2B; P53R2; MTDPS8A; MTDPS8B; P53R2; p53R2] |
Gene, Accession # | [RRM2B], Gene ID: 50484, NCBI: BAA92434, UniProt: Q7LG56 |
Catalog # | MBS150957 |
Price | $375 |
Order / More Info | p53R2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |