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Antigenic Specificity | Cleaved-PARP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PARP (Cleaved-Asp214) Antibody detects endogenous levels of fragment of activated PARP resulting from cleavage adjacent to Asp214. Nvolved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. |
Immunogen | n/a |
Other Names | [ADP-ribosyltransferase 1; ADPRT; ADPRT1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) pol; poly [ADP-ribose] polymerase 1; poly[ADP-ribose] synthetase 1; PPOL] |
Gene, Accession # | Gene ID: 142, NCBI: NP_001609.2, UniProt: P09874 |
Catalog # | MBS9404799 |
Price | $255 |
Order / More Info | Cleaved-PARP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |