Dok1 (Tyr-362), phospho-specific Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Dok1 (Tyr-362), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was cross-adsorbed to a phosphotyrosine peptide before affinity purification using phospho-Dok1 (Tyr-362) peptide. The purified antibody detects a band at 62 kDa* corresponding to Dok1 in western blots of human Jurkat cells, but does not detect this band after alkaline phosphatase treatment. Similar to Dok1 (Ser-450) antibody, this antibody also detects an 80 kDa band that has not been identified. Doks are a family of adaptor proteins that recruit SH2-containing molecules involved in various cell signaling pathways. Six Dok proteins (Dok1 to Dok6) have been identified and each has an N-terminal pleckstrin homology domain, a central phosphotyrosine binding domain, and a C-terminal region containing multiple tyrosine residues. W |
| Immunogen | Immunogen: Phospho-Dok1 (Tyr-362) synthetic peptide (coupled to KLH) corresponds to amino acids surrounding tyrosine 362 in human Dok1. This sequenceis conserved in Dok1 from rat and mouse (Tyr-361), and has high homology to Dok2 (Tyr-337). The site is not conserved in other Dok family members. |
| Other Names | [p62DOK], [DOK1; P62DOK; MGC117395; MGC138860] |
| Gene, Accession # | Gene ID: 1796, NCBI: NP_001372.1, UniProt: Q53GP8 |
| Catalog # | MBS472020 |
| Price | $385 |
| Order / More Info | Dok1 (Tyr-362), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Noguchi, T. et al. (1999) EMBOJ 18(7):1748.• Kashige, N. et al. (2000) Proc. Nat. Acad. Sci. 97(5):2093.• Lee, S. et al. (2004) Proc. Nat. Acad. Sci. 101(50):17416.• Woodring, P.J. (2004) J Cell Biol. 165(4):493. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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