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Antigenic Specificity | CREB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti CREB1 antibody recognizes cyclin AMP-responsive element-binding protein 1, also known as CREB-1. It belongs to the family of transcription factors mediating gene expression in neuronal and non-neuronal cells (Lonze et al. 2002). CREB1 is activated in response to growth factor stimulation, electrical stimulation and synaptic activity (Shaywitz and Greenberg 1999). In mice, disruption of CREB1 function results in neurodegeneration (Mantamadiotis et al. 2002). CREB1 is overexpressed in gliomas and promotes gliomagenesis acting as a modulator of oncogenic microRNA-23a (Tan et al. 2012). CREB1, together with SETD2, contribute to cisplatin cytotoxicity regulating the ERK signalling pathway (Kim et al. 2018). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CREB1. |
Other Names | [CREB1], [CREB1; CREB1; CREB; CREB-1; CREB-1] |
Gene, Accession # | [CREB1], Gene ID: 1385, NCBI: NP_004370.1, UniProt: P16220 |
Catalog # | MBS225602 |
Price | $375 |
Order / More Info | CREB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |