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Antigenic Specificity | TIMP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | esultant inhibition of proteinase function (1,2). In addition to MMP inhibition, TIMPs have also been shown to interact with various membrane receptors on the cell surface. Some of these interactions include: TIMP1 with CD63, TIMP2 with alpha3beta1 integrin, and TIMP3 with VEGFR2, all of which result in distinct cellular effects (3). TIMPs are involved in a wide variety of biological functions, such as tumor angiogenesis and progression (4,5), wound healing, and vascular remodeling (6,7). Mutations in TIMP3 are associated with Sorsby's fundus dystrophy (8,9). |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [CSC-21K; TIMP2], [TIMP2; TIMP2; DDC8; CSC-21K; KIAA1731NL; TIMP-2] |
Gene, Accession # | [TIMP2], Gene ID: 7077, NCBI: P16035.2, UniProt: P16035 |
Catalog # | MBS126326 |
Price | $200, $275, $430 |
Order / More Info | TIMP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |