PARD3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PARD3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total PARD3 protein. Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions By similarity. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.Joberty G., Nat. Cell Biol. 2:531-539(2000).Fang C.M., Cell Res. 11:223-229(2001).Kohjima M., Biochem. Biophys. Res. Commun. 299:641-646 |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human PARD3. |
| Other Names | [Partitioning-defective 3 homolog; PARD-3; PAR-3; Atypical PKC isotype-specific-interacting protein; ASIP] |
| Gene, Accession # | [PARD3], Gene ID: 56288, NCBI: NP_001171714.1, UniProt: Q8TEW0 |
| Catalog # | MBS9414562 |
| Price | $200, $255 |
| Order / More Info | PARD3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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