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Antigenic Specificity | RFC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Replication factor C subunit 1(RFC1) detection. Tested with WB, IHC-P in Human. Background: RFC(Replication Factor C), also called activator-1, is a multimeric primer-recognition protein consisting of 5 distinct subunits of 145, 40, 38, 37, and 36.5 kD. Human RFC was purified from extracts of HeLa cells as a host factor essential for the in vitro replication of simian virus 40(SV40) DNA. RFC, in the presence of ATP, assembles proliferating-cell nuclear antigen and DNA polymerase-delta or polymerase-epsilon on primed DNA templates. Tight interfacial coordination of the ATP analog ATP-gamma-S by RFC resulted in a spiral arrangement of the ATPase domains of the clamp loader above the PCNA ring. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human RFC1 (46-64aa NSSRKEDDFKQKQPSKKKR). |
Other Names | [Replication factor C subunit 1; replication factor C(activator 1) 1, 145kDa; A1 140 kDa subunit; A1; A1 P145 Activator 1 large subunit; Activator 1 140 kDa subunit; Activator 1 large subunit; Activator 1 subunit 1; DNA binding Protein PO GA; DNA-binding protein PO-GA; MHC binding factor beta; MHCBFB; PO GA; RECC1; Replication factor C(activator 1) 1, 145kDa; Replication factor C 140 kDa subunit; Replication factor C; Replication factor C large subunit; Replication factor C subunit 1; Replication factor C1; RF-C 140 kDa subunit; RFC; RFC1; RFC1_HUMAN; RFC140; RFC140 Replication Factor C 140 kDa subunit], [RFC1; RFC1; A1; RFC; PO-GA; RECC1; MHCBFB; RFC140; RFC140; A1 140 kDa subunit; RF-C 140 kDa subunit; RFC140] |
Gene, Accession # | [RFC1], Gene ID: 5981, NCBI: P35251.4, UniProt: P35251 |
Catalog # | MBS175156 |
Price | $315 |
Order / More Info | RFC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |