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Antigenic Specificity | TrkA |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TrkA, also known as NTRK1, MTC, TRK, TRK1. It is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
Immunogen | Immunogen: Purified recombinant extracellular fragment of human TrkA (aa33-423) fused with hIgGFc tag expressed in HEK293 cell line. |
Other Names | [NTRK1; MTC; TRK; TRK1], [NTRK1; NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA;; Trk-A] |
Gene, Accession # | [TrkA], Gene ID: 4914, NCBI: NP_001007793.1, UniProt: P04629 |
Catalog # | MBS850155 |
Price | $280 |
Order / More Info | TrkA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |