NR1H2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NR1H2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, porcine |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NR1H2 antibody detects endogenous levels of NR1H2. Function: Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920). Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (Pu |
| Immunogen | Immunogen: A synthesized peptide derived from human NR1H2. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (100%) |
| Other Names | [Liver X nuclear receptor beta; Liver X receptor beta; LX receptor beta; LXR b; LXR beta; LXRB; NER; NER I; NER1; NR1H 2; NR1H2; NR1H2_HUMAN; Nuclear orphan receptor LXR beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; OR-1; Oxysterols receptor LXR-beta; RIP15; Steroid hormone nuclear receptor NER; Ubiquitously-expressed nuclear receptor; UNR] |
| Gene, Accession # | [NR1H2], Gene ID: 7376, NCBI: NP_001243576.1, UniProt: P55055 |
| Catalog # | MBS9603354 |
| Price | $240, $280 |
| Order / More Info | NR1H2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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