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Antigenic Specificity | TRIP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kB activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the center of human TRIP6. |
Other Names | [Thyroid hormone receptor interactor 6, Opa-interacting protein 1, OIP-1, Zyxin-related protein 1, ZRP-1] |
Gene, Accession # | [TRIP6], Gene ID: 7205, NCBI: NP_003293 |
Catalog # | MBS9408634 |
Price | $320 |
Order / More Info | TRIP6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |