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Antigenic Specificity | GABA B Receptor 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | 0.55-0.75 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Will label various GABA B subunit 2 variants. BIOTIN-Conjugated Gamma-aminobutyric acid receptor subunit beta-2 Antibody N-epitope. Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1-50 on human gamma-aminobutyric acid A receptor beta 2 protein. Expression: Isoform 1 and isoform 2 show reduced expression in schizophrenic brain. Isoform 3 shows increased expression in schizophrenic and bipolar disorder brains while isoform 4 shows reduced expression. |
Other Names | [GABA-B-R2; Gamma aminobutyric acid (GABA) B receptor 2; Gb1; GPRC3A; Seven transmembrane helix receptor], [GABRB2; GABRB2] |
Gene, Accession # | [GABA B], Gene ID: 2561, NCBI: ACY69094.1, UniProt: P47870 |
Catalog # | MBS541658 |
Price | $495 |
Order / More Info | GABA B Receptor 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |