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Antigenic Specificity | Caspase 9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase family of cysteine proteases plays a key role in apoptosis. Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase-9/Apaf-1. The complex processes procaspase-9 into a large subunit and small by self-cleavage at D315. Activated caspase-9 further cleaves other caspase members including caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. In addition to self-cleavage, procaspase-9 can also be cleaved in vivo by caspase-3 at D330. The process served as a positive feedback to amplify the apoptotic signal in caspase activation pathway. |
Immunogen | Immunogen: Caspase 9 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 290 of mouse caspase-9 as the immunogen. |
Other Names | [Rabbit Caspase 9; Caspase 9; Caspase 9; Apoptotic protease-activating factor 3; Apoptotic protease Mch-6; CASP-9; ICE-like apoptotic protease 6; Caspase 9; Caspase -9; Apaf-3; ICE-LAP6; Caspase -9; EC 3.4.22.62; Caspase 9; Caspase 9] |
Gene, Accession # | [CASP-9], Gene ID: 373560 |
Catalog # | MBS5311183 |
Price | $445 |
Order / More Info | Caspase 9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |