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Antigenic Specificity | BACE-2, |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BACE-2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE-1 (Memapsin 2). While BACE1 processes the amyloid precursor protein (APP) at a key step in generating the beta-amyloid peptide and presumably causes Alzheimer's disease (AD), BACE2 has not been demonstrated to be directly involved in APP processing, and its physiological functions remain to be determined. In vivo, BACE-2 is expressed as a precursor protein containing pre-, pro-, protease, transmembrane, and cytosolic domains/peptides. |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids near the N-terminus of Human BACE-2. |
Other Names | [bace-2, putative, partial; Bace-2, putative; Bace-2, putative], [IscW_ISCW007278] |
Gene, Accession # | [BACE-2], NCBI: EEC10954.1 |
Catalog # | MBS555141 |
Price | $485 |
Order / More Info | BACE-2, Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |