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Antigenic Specificity | Human INTERLEUKIN-23 (C-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects an epitope within the C-terminal (CT) domain of human interleukin-23 (IL-23), a 21kD heterodimeric cytokine structurally related to IL-12. IL-23 is composed of a p19 subunit encoded by the IL23A gene, and a p40 subunit of interleukin-12 (IL12B). IL-23 is expressed mainly by activated macrophages and dendritic cells, and plays an important role in bridging innate and adaptive responses.. . IL-23 activates a subset of T cells called Th17 cells, which are characterised by the production of interleukin-17. The IL-23/IL-17 pathway is essential for the induction and maintenance of brain and joint inflammatory autoimmune diseases, including Guillain Barre Syndrome, Multiple sclerosis and rheumatoid arthritis. MBS221462 detects |
Immunogen | Immunogen: A 14 amino acid peptide from near the carboxy-terminus of human IL-23. Histology Positive Control Tissue: Raji cells. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human IL-23 (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [interleukin-23 subunit alpha; Interleukin-23 subunit alpha; interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; IL-23p19; JKA3 induced upon T-cell activation; interleukin 23 p19 subunit; interleukin-23 subunit p19; interleukin-six, G-CSF related factor; interleukin 23, alpha subunit p19; Interleukin-23 subunit p19; IL-23p19], [IL23A; IL23A; P19; SGRF; IL-23; IL-23A; IL23P19; SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19] |
Gene, Accession # | Gene ID: 51561, NCBI: NP_057668.1, UniProt: Q9NPF7 |
Catalog # | MBS221462 |
Price | $470 |
Order / More Info | Human INTERLEUKIN-23 (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |