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Antigenic Specificity | Phospho-MAK (Thr1579) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MAK (Thr1579) Antibody detects endogenous levels of MAK only when phosphorylated at Thr1579. Description: Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells.Post Translational Modifications: Autophosphorylated. Phosphorylated on serine and threonine residues.Subunit Structure: Interacts with RP1 (By similarity). Interacts with AR and CDK20. Found in a complex containing MAK, AR and NCOA3. Interacts with FZR1 ( |
Immunogen | Immunogen: A synthesized peptide derived from human MAK around the phosphorylation site of Thr1579. Tissue Specificity: Expressed in prostate cancer cell lines at generally higher levels than in normal prostate epithelial cell lines. Isoform 1 is expressed in kidney, testis, lung, trachea, and retina. Isoform 2 is retina-specific where it is expressed in rod and cone photoreceptors. |
Other Names | [intestinal cell kinase; dJ417M14.2; fj04c02; Ick; Mak; MAK_HUMAN; Male germ cell associated kinase; Male germ cell-associated kinase; male germ cell-associated kinase retinal-enriched isoform; OTTHUMP00000016025; Rck; RP62; Serine/threonine protein kinase MAK; Serine/threonine-protein kinase MAK; testicular secretory protein Li 28; wu:fj04c02; zgc:56603] |
Gene, Accession # | [MAK], Gene ID: 4117, NCBI: NP_001229314.1, UniProt: P20794 |
Catalog # | MBS9610619 |
Price | $225, $280, $340 |
Order / More Info | Phospho-MAK (Thr1579) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |