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Antigenic Specificity | RAB7A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes (or vacuoles) and autophagosomes. Plays a role in the maturation and |
Immunogen | Immunogen: Recombinant human Ras-related protein Rab-7a protein (110-177AA) |
Other Names | [Ras-related protein Rab-7a; RAB7A; RAB7] |
Gene, Accession # | [RAB7A], Gene ID: 7879, NCBI: NP_004628.4, UniProt: P51149 |
Catalog # | MBS7048984 |
Price | $160, $235 |
Order / More Info | RAB7A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |