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Antigenic Specificity | 14-3-3 theta/tau |
Clone | [3B9] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, bovine |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | At least seven isoforms comprise the highly conserved 14-3-3 family of homo- and heterodimeric proteins that are abundantly expressed in all eukaryotic cells. Although more than seven isoforms of 14-3-3 have been described, some redundancies have appeared upon sequencing. The 14-3-3s are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. By interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle and, through interaction with Bad, prevents apoptosis. Other proteins that have been shown to bind to 14-3-3s include members of the protein kinase C family, Cbl, IRS-1, polyoma middle-T antigen, nitrate reductase, S-raf and the IGF-1 receptor. Detection of 14-3-3 |
Immunogen | Immunogen: Recombinant 14-3-3 / protein |
Other Names | [mouse 14-3-3 theta/tau; theta tau], [YWHAQ; YWHAQ; 1C5; HS1; 14-3-3] |
Gene, Accession # | [14-3-3 theta/tau], Gene ID: 10971, NCBI: NP_006817.1, UniProt: P27348 |
Catalog # | MBS395059 |
Price | $340 |
Order / More Info | 14-3-3 theta/tau Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |