Edit |   |
---|---|
Antigenic Specificity | BACE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BACE Polyclonal Antibody detects endogenous levels of BACE protein. BACE1 encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. |
Immunogen | Immunogen: Synthesized peptide derived from human BACE around the non-phosphorylation site of S498 |
Other Names | [Rabbit BACE; BACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2] |
Gene, Accession # | [BACE], Gene ID: 23621, NCBI: NP_001193977.1, UniProt: P56817 |
Catalog # | MBS9705015 |
Price | $130, $220, $325 |
Order / More Info | BACE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |