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Antigenic Specificity | DRD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DRD2 antibody detects endogenous levels of total DRD2. Function: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.Subunit Structure: Forms homo-and heterooligomers with DRD4. The interaction with DRD4 may modulate agonist-induced downstream signaling. Interacts with GPRASP1, PPP1R9B and CLIC6 (By similarity). Interacts with CADPS and CADPS2. Interacts with ARRB2 (By similarity). Interacts with KCNA2 (By similarity). Interacts with GNAI2 isoform sGi2, the interaction allows the creation of an intracellular pool of DRD2 that can be released to cell surface upon agonist stimulation. Interacts with HTR2A.Similarity: Belongs to the G-protein coupled receptor 1 family. |
Immunogen | Immunogen: A synthesized peptide derived from human DRD2 Subcellular Location: Cell Membrane Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
Other Names | [D(2) dopamine receptor; D2 dopamine receptor; D2DR; D2R; Dopamine D2 receptor; Dopamine receptor D2; DRD 2; DRD2; DRD2_HUMAN] |
Gene, Accession # | [DRD2], Gene ID: 1813, NCBI: NP_000786.1, UniProt: P14416 |
Catalog # | MBS9603069 |
Price | $240, $280 |
Order / More Info | DRD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Liu Y, Geng L, Zhang J, Wang J, Zhang Q, Duan D, Zhang Q; Journal: Mar Drugs. Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway. |