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Antigenic Specificity | PDCD6 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PDCD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human PDCD6. Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in t |
Immunogen | n/a |
Other Names | [Programmed cell death protein 6; Apoptosis-linked gene 2 protein; Probable calcium-binding protein ALG-2; PDCD6; ALG2] |
Gene, Accession # | [PDCD6], Gene ID: 10016, NCBI: NP_001254485.1, UniProt: O75340 |
Catalog # | MBS9214299 |
Price | $165, $370 |
Order / More Info | PDCD6 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Ganjei J.K.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases. Urcelay E.,et al.Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. Schmutz J.,et al.Nature 431:268-274(2004). |