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Antigenic Specificity | PCSK9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse, gorilla |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~74 kDa of human PCSK9 protein. It also reacts with mouse and rat. The other species are not tested. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a member of the serine protease family with a critical role in cholesterol metabolism by controlling the levels of low density lipoprotein (LDL) particles that circulate in the bloodstream. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in LDL cholesterol levels. PCSK9 is expressed in various tissues such as liver, kidney, lung, spleen, etc. Human PCSK9 precursor is 692 aa protein with 74kDa molecular weight. Its mature form has molecular weight ranging of 62-66 kDa in the tissues. |
Immunogen | Antigen Preparation: A synthetic peptide derived from 100aa-300aa of Human PCSK9 protein. This sequence is identical among human, rat, mouse, gorilla, etc. |
Other Names | [Rabbit PCSK9; Proprotein convertase subtilisin/kexin type 9 (PCSK9) Proprotein concertase PC9; Subtilisin/Kexin-like protease PC9; FH3; NARC1], [PCSK9; PCSK9; FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3; NARC1] |
Gene, Accession # | [PCSK9], Gene ID: 255738, NCBI: NP_777596.2, UniProt: Q8NBP7 |
Catalog # | MBS462174 |
Price | $285 |
Order / More Info | PCSK9 Antibody from MYBIOSOURCE INC. |
Product Specific References | Lopez D (2008) PCSK9: an enigmatic protease. Biochim Biophys Acta. 1781 (4): 184-91. |