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Antigenic Specificity | APC |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | IgG |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Rabbit IgG Monoclonal antibody for P25054 detection. Tested positive for WB IHC IF/IF IP in Human Rat |
Immunogen | Immunogen: A synthesized peptide derived from human APC Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of micr |
Other Names | [adenomatous polyposis coli protein isoform b; Adenomatous polyposis coli protein; adenomatous polyposis coli protein; APC, WNT signaling pathway regulator; Deleted in polyposis 2.5] |
Gene, Accession # | [APC], Gene ID: 324, NCBI: NP_000029.2, UniProt: P25054 |
Catalog # | MBS1751890 |
Price | $160, $340, $340 |
Order / More Info | APC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |