NAK/TBK1 (N-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NAK/TBK1 (N-term) |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Serine/threonine kinase that plays an essential role in regulating inflammatory responses to foreign agents. Following activation of toll-like receptors by viral or bacterial components, associates with TRAF3 and TANK and phosphorylates interferon regulatory factors (IRFs) IRF3 and IRF7 as well as DDX3X. This activity allows subsequent homodimerization and nuclear translocation of the IRFs leading to transcriptional activation of pro-inflammatory and antiviral genes including IFNA and IFNB. In order to establish such an antiviral state, TBK1 form several different complexes whose composition depends on the type of cell and cellular stimuli. Thus, several scaffolding molecules including FADD, TRADD, MAVS, AZI2, TANK or TBKBP1/SINTBAD can be |
| Immunogen | Immunogen: A synthesized peptide derived from human NAK/TBK1 (N-term). Subcellular Localization: Cytoplasm. Upon mitogen stimulation or triggering of the immune system, TBK1 is recruited to the exocyst by EXOC2. Tissue Specificity: Ubiquitous with higher expression in testis. Expressed in the ganglion cells, nerve fiber layer and microvasculature of the retina. |
| Other Names | [Serine/threonine-protein kinase TBK1; 2.7.11.1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1; TBK1; NAK], [TBK1; TBK1; NAK; T2K; FTDALS4; NAK] |
| Gene, Accession # | [NAK/TBK1], Gene ID: 29110, NCBI: NP_037386.1, UniProt: Q9UHD2 |
| Catalog # | MBS179228 |
| Price | $160, $340, $340 |
| Order / More Info | NAK/TBK1 (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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