FHIT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFHIT
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein A purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
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DescriptionThe candidate tumor suppressor gene, FHIT (Fragile histidine triad protein), encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5'''-P1,P3-triphosphate in vitro and mutation of a central histidine abolishes hydrolase activity (PMID:9391102). FHIT has a major role in regulating beta-catenin-mediated gene transcription.
ImmunogenImmunogen: FHIT fusion protein ag14471
Other Names[AP3A hydrolase; AP3Aase; Bis(5 adenosyl) triphosphatase; Dinucleosidetriphosphatase; FHIT; FRA3B; fragile histidine triad gene]
Gene, Accession #[FHIT], Gene ID: 2272, NCBI: NP_001159715.1, UniProt: P49789
Catalog #MBS2540193
Price$220, $290, $435
Order / More InfoFHIT Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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