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Antigenic Specificity | FHIT |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The candidate tumor suppressor gene, FHIT (Fragile histidine triad protein), encompasses the common human chromosomal fragile site at 3p14.2, the hereditary renal cancer translocation breakpoint, and cancer cell homozygous deletions. Fhit hydrolyzes dinucleotide 5',5'''-P1,P3-triphosphate in vitro and mutation of a central histidine abolishes hydrolase activity (PMID:9391102). FHIT has a major role in regulating beta-catenin-mediated gene transcription. |
Immunogen | Immunogen: FHIT fusion protein ag14471 |
Other Names | [AP3A hydrolase; AP3Aase; Bis(5 adenosyl) triphosphatase; Dinucleosidetriphosphatase; FHIT; FRA3B; fragile histidine triad gene] |
Gene, Accession # | [FHIT], Gene ID: 2272, NCBI: NP_001159715.1, UniProt: P49789 |
Catalog # | MBS2540193 |
Price | $220, $290, $435 |
Order / More Info | FHIT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |