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Antigenic Specificity | Mouse EphB4 |
Clone | [6A14] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) - Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was selected for its ability to detect mouse EphB4 in western blots. In this format, this antibody does not cross-react with recombinant mouse EphA2, EphA3, EphA4, EphA6, EphA7 and EphB6. EphB4, also known as Htk, Myk1, Tyro11, and Mdk2, is a member of the Eph receptor family which binds members of the ephrin ligand family. There are two classes of receptors, designated A and B. Both the A and B class receptors have an extracellular region consisting of a globular domain, a cysteinerich domain, and two fibronectin type III domains. This is followed by the transmembrane region and cytoplasmic region. The cytoplasmic region contains a juxtamembrane motif with two tyrosine residues, which are the major autophosphorylation sites, |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with recombinant mouse EphB4 extracellular domain. IgG1 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
Other Names | [mouse EphB4 (#6A14)], [Ephb4; Ephb4; Htk; MDK2; Myk1; Tyro11; AI042935] |
Gene, Accession # | [EphB4], Gene ID: 13846, NCBI: NP_001153043.1, UniProt: Q8C8K1 |
Catalog # | MBS690258 |
Price | $490 |
Order / More Info | Mouse EphB4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |