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Antigenic Specificity | IKKalpha / IKK-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: IKKalpha (IkB kinase-alpha or IKK-1) is part of a large protein complex responsible for the inducible phosphorylation of IkB proteins. Human IKK-alpha is an 85 kDa peptide that has been shown to activate NFkB by phosphorylation of IkB proteins. IKKalpha interacts with its upstream kinase, NIK, and its downstream substrate, the IkB proteins. Mutations of IKKalpha in its kinase domain lead to a dominant-negative phenotype that suppresses TNF-alpha and IL-1beta induced NFkB activation. |
Immunogen | Immunogen: E. coli expressed recombinant human IKKa |
Other Names | [IKK-alpha; IKKA; IKK-A; IKBKA; NFKBIKA; TCF16; CHUK; IKK1], [CHUK; CHUK; IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha; IKKA; TCF16; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; IKK1; NFKBIKA; TCF-16] |
Gene, Accession # | [IKKalpha/IKK-1], Gene ID: 1147, NCBI: NP_001269 |
Catalog # | MBS841283 |
Price | $290 |
Order / More Info | IKKalpha / IKK-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |