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Antigenic Specificity | XPG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: XPG Polyclonal Antibody detects endogenous levels of XPG protein. ERCC5 encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. DNA repair protein complementing XP-G cells may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by sever |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human XPG at AA range: 100-180 |
Other Names | [Rabbit XPG; ERCC5; ERCM2; XPG; XPGC; DNA repair protein complementing XP-G cells; DNA excision repair protein ERCC-5; Xeroderma pigmentosum group G-complementing protein] |
Gene, Accession # | [XPG], Gene ID: 2073, NCBI: NP_000114.2, UniProt: P28715 |
Catalog # | MBS9703377 |
Price | $130, $220, $325 |
Order / More Info | XPG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |