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Antigenic Specificity | 14-3-3 Theta |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. |
Immunogen | Immunogen: A synthesized peptide derived from human 14-3-3 Theta. Subcellular Localization: Cytoplasm. In neurons, axonally transported to the nerve terminals. Tissue Specificity: Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. |
Other Names | [14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1; YWHAQ], [YWHAQ] |
Gene, Accession # | [14-3-3 Theta], Gene ID: 10971, NCBI: NP_006817.1, UniProt: P27348 |
Catalog # | MBS179991 |
Price | $160, $340, $340 |
Order / More Info | 14-3-3 Theta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |