BACE Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | BACE |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | ion exchange purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BACE Antibody: Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by two proteases. APP is first cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide, which is deposited in the brains of all suffers of Alzheimer's disease. The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme |
| Immunogen | Immunogen: BACE antibody was raised against a peptide corresponding to 17 amino acids at the carboxy terminus of human BACE. Buffer: BACE Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [BACE; ASP2; BACE; HSPC104; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; beta-site APP-cleaving enzyme 1], [BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2; Beta-site APP cleaving enzyme 1] |
| Gene, Accession # | [BACE1], Gene ID: 23621, NCBI: AF190725, UniProt: P56817 |
| Catalog # | MBS150291 |
| Price | $375 |
| Order / More Info | BACE Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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