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Antigenic Specificity | Mouse Cbx7 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Cbx7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-178 amino acids from the C-terminal region of human Mouse Cbx7. Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trimethylated |
Immunogen | n/a |
Other Names | [Chromobox protein homolog 7; Cbx7; D15Ertd417e] |
Gene, Accession # | [Cbx7], Gene ID: 52609, NCBI: NP_659060.1, UniProt: Q8VDS3 |
Catalog # | MBS9212668 |
Price | $165, $370 |
Order / More Info | Mouse Cbx7 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Gil J.,et al.Nat. Cell Biol. 6:67-72(2004). Bernstein E.,et al.Mol. Cell. Biol. 26:2560-2569(2006). Yap K.L.,et al.Mol. Cell 38:662-674(2010). |