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Antigenic Specificity | MEK 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody recognizes 45 kDa phospho-MEK 1 (Ser217/221). It does not detect the unphosphorylated protein. MEK 1 is a 43 kDa dual specificity protein kinase that phosphorylates threonine and tyrosine residues on MAP kinases such as Erk 1 and 2. Mek1 and Mek2 are involved in a diverse array of cellular processes such as stress activated response, apoptosis, cytokine induced cell proliferation, and DNA recombination during meiosis. Mek1 and Mek2 are activated by phosphorylation on serine 218 and 222 by serine threonine kinase, Raf 1, which is part of the p21ras signal transduction pathway. |
Immunogen | n/a |
Other Names | [Rabbit MEK 1; MEK 1; MEK 1; MAP kinase 1; MEK 1; MAP kinase; MEK 1; MEK-1; Phospho-Mek-1/2; Microtubule associated protein 2 kinase; MEK 1; MEK-1; Mitogen activated protein kinase; ERK kinase 1] |
Gene, Accession # | [MEK 1], NCBI: ALE20556.1 |
Catalog # | MBS5309132 |
Price | $735 |
Order / More Info | MEK 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |