Edit |   |
---|---|
Antigenic Specificity | SCARB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SCARB1 Antibody: Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member |
Immunogen | Immunogen: SCARB1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SCARB1. Buffer: SCARB1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [SCARB1; CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; CLA1; Scavenger receptor class B member 1; CD36 and LIMPII analogous 1; scavenger receptor class B, member 1], [SCARB1; SCARB1; CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; CD36L1; CLA1; SRB1; CLA-1] |
Gene, Accession # | [SCARB1], Gene ID: 949, NCBI: Q8WTV0.1, UniProt: Q8WTV0 |
Catalog # | MBS150134 |
Price | $375 |
Order / More Info | SCARB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |