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Antigenic Specificity | CTCF |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1,k |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | 0.57 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CTCF antibody is generated from a mouse immunized with a recombinant protein between 445-727 amino acids from human CTCF. Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. Seems to act as tumor sup |
Immunogen | n/a |
Other Names | [Transcriptional repressor CTCF; 11-zinc finger protein; CCCTC-binding factor; CTCFL paralog; CTCF; Purified Mouse (Mab)] |
Gene, Accession # | [CTCF], Gene ID: 10664, NCBI: P49711.1, UniProt: P49711 |
Catalog # | MBS9217318 |
Price | $165, $370 |
Order / More Info | CTCF Antibody from MYBIOSOURCE INC. |
Product Specific References | Filippova G.N.,et al.Mol. Cell. Biol. 16:2802-2813(1996). Filippova G.N.,et al.Genes Chromosomes Cancer 22:26-36(1998). Filippova G.N.,et al.Cancer Res. 62:48-52(2002). Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. |