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Antigenic Specificity | ESA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ESA antibody detects endogenous levels of total ESA. Description: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.Subunit Structure: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2 (By similarity). Interacts with ECPAS.Post-translational Modifications: ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells.Similarity: Belongs to the band 7/mec-2 family. Flot |
Immunogen | Immunogen: A synthesized peptide derived from human ESA Subcellular Location: Cell Membrane. Membrane > Caveola. Endosome. Membrane-associated protein of caveolae. Tissue Specificity: In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes. |
Other Names | [ECS-1; ECS1; Epidermal surface antigen 1; Epidermal surface antigen; ESA; ESA1; Flot2; FLOT2_HUMAN; Flotillin 2 (epidermal surface antigen 1); Flotillin-2; M17S1; Membrane component chromosome 17 surface marker 1; Membrane component chromosome 17 surface marker 1 homolog; membrane component, chromosome 17, surface marker 1 (35kD protein identified by ECS-1); Membrane component, chromosome 17, surface marker 1; REG-1; Reggie-1; Reggie-2] |
Gene, Accession # | [ESA], Gene ID: 2319, NCBI: NP_004466.2, UniProt: Q14254 |
Catalog # | MBS9601380 |
Price | $240, $280 |
Order / More Info | ESA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |