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Antigenic Specificity | FKBPL |
Clone | [170] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FKBPL, also named as DIR1, NG7 and WISp39, has similarity to the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is thought to have a potential role in the induced radioresistance, probably by increasing the rate of DNA repair in cells exposed to X rays. Also it appears to have some involvement in general stress response in the control of the cell cycle. It regulates p21 protein stability by binding to Hsp90 and p21. Breast cancer cells stably overexpressing FKBPL became dependent on estrogen for their growth and were dramatically more sensitive to the antiestrogens tamoxifen and fulvestrant, whereas FKBPL knockdown reverses this phenoty |
Immunogen | Immunogen: Fusion protein of FKBPL |
Other Names | [DIR1; FK506 binding protein like; FK506-binding protein-like; Fkbpl; FKBPL; NG7; OTTHUMP00000029170; WAF 1/CIP1 stabilizing protein 39; WAF-1/CIP1 stabilizing protein 39; WISP39] |
Gene, Accession # | [FKBPL], Gene ID: 63943, NCBI: NP_071393.2, UniProt: Q9UIM3 |
Catalog # | MBS2542285 |
Price | $220, $290, $435 |
Order / More Info | FKBPL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |