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Antigenic Specificity | Mouse VEGFR-2/KDR, Antagonistic |
Clone | monoclonal |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Stimulation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes mVEGFR-2 (~220-230kDa) in Western blot and it shows no cross-reactivity with mVEGFR-1. VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated |
Immunogen | n/a |
Other Names | [Antagonistic of mouse VEGFR-2], [Kdr; Kdr; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07; Flk-1; Flk1; VEGFR-2; FLK-1] |
Gene, Accession # | [VEGFR-2/KDR], Gene ID: 16542, NCBI: P35918.1, UniProt: P35918 |
Catalog # | MBS690808 |
Price | $895 |
Order / More Info | Mouse VEGFR-2/KDR, Antagonistic Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |