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Antigenic Specificity | ADAM10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Proinflammatory cytokine tumor necrosis factoralpha (TNF-alpha) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-alpha, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated |
Immunogen | Immunogen: Synthetic peptide corresponding to residue surrounding amino acid 735 of human ADAM10 |
Other Names | [MADM; CDw156; CD156c; kuz; EC 3.4.24.81; HsT18717], [ADAM10; ADAM10; RAK; kuz; AD10; AD18; MADM; CD156c; HsT18717; KUZ; MADM; ADAM 10] |
Gene, Accession # | [ADAM10], Gene ID: 102, NCBI: AAC51766 |
Catalog # | MBS840624 |
Price | $305 |
Order / More Info | ADAM10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |