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Antigenic Specificity | NUAK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NUAK2 antibody detects endogenous levels of total NUAK2. Function: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.Post-translational Modifications: Phosphorylated at Thr-208 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Autophosphorylated in vitro.Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfami |
Immunogen | Immunogen: A synthesized peptide Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog Similarity: Pig (89%), Horse (100%), Sheep (89%), Rabbit (100%), Dog (100%) |
Other Names | [DKFZp434J037; DKFZp686F01113; FLJ90349; NUAK family SNF1 like kinase 2; NUAK family SNF1-like kinase 2; Nuak2; NUAK2_HUMAN; Omphalocele kinase 2; SNARK; SNF1/AMP activated protein kinase; SNF1/AMP kinase related kinase; SNF1/AMP kinase-related kinase] |
Gene, Accession # | [NUAK2], Gene ID: 81788, NCBI: NP_112214.2, UniProt: Q9H093 |
Catalog # | MBS9604185 |
Price | $240, $280 |
Order / More Info | NUAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |