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Antigenic Specificity | Mouse CASP12 / Caspase 12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: peptide corresponding to amino acids 100 to 116 of murine caspase-12. Caspases mediate essential key proteolytic events in inflammatory cascades and the apoptotic cell death pathway. Caspase 12 is involved in the apoptosis triggered by a stress on the endoplasmic reticulum. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. |
Immunogen | Immunogen Description: Synthetic peptide from mouse CASP12 / Caspase 12. |
Other Names | [CASP12 / Caspase 12 (aa100-116) IHC-plus; CASP12; Caspase 12 pseudogene 1; Caspase 12; CASP-12; Caspase 12 (gene/pseudogene); Inactive caspase-12; CASP12P1; Mouse CASP12; Caspase 12], [CASP12; CASP12; CASP-12; CASP12P1; CASP-12] |
Gene, Accession # | [CASP12], Gene ID: 100506742, NCBI: NP_001177945.2, UniProt: Q6UXS9 |
Catalog # | MBS242557 |
Price | $530 |
Order / More Info | Mouse CASP12 / Caspase 12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |