Edit |   |
---|---|
Antigenic Specificity | MPZL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenes |
Immunogen | Immunogen: Recombinant protein of human MPZL2 (NP 005788.1). |
Other Names | [myelin protein zero-like protein 2; Myelin protein zero-like protein 2; myelin protein zero-like protein 2; myelin protein zero like 2; Epithelial V-like antigen 1] |
Gene, Accession # | [MPZL2], Gene ID: 10205, NCBI: NP_005788.1, UniProt: O60487 |
Catalog # | MBS8566576 |
Price | $280 |
Order / More Info | MPZL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |